This morning i was presented with the perpetual log-off. When a user ran a remote app, the normal log in process would happen, however instead of the remote app appearing, it would then immediately log off the user.
I noted a system restart in the middle of the night for maintenance and reviewed the installed updates. One of these updates, was also mentioned on a StackExchange entry two hours prior by someone experiencing exactly the same issue.
If you are having the same problem, you may want to look into Microsofts KB3004394 update.
This issue, doesn't affect full remote desktop sessions - just the remote apps.
I have scheduled to remove the update this evening and test to see if this resolves the issue.
Stack Exchange entry: Rds RemoteApp logged off immediately after preparing desktop (under details) msi and rdp
Microsoft KB Entry: December 2014 update for Windows Root Certificate Program in Windows